Leicester beat Southampton to open seven-point gap at the top.
Swansea City came from behind to beat Arsenal 2-1 and Tottenham Hotspur's misery continued with a 2-1 home defeat by Stoke City, making it a nightmare Sunday for north London.
Images from the English Premier League matches played on Saturday
English football clubs splurged on the final day of the transfer window, laying out 210 million pounds to take total gross spending to a record-high 1.4 billion pounds as the Premier League again flexed its unrivalled financial muscles.
Spain and Portugal played out an entertaining 0-0 draw on Friday as both sides prepared for this month's European Championship.
On Sunday the Ukrainian Tennis Federation urged the sport's governing body the International Tennis Federation (ITF) to immediately expel Russia and Belarus from the organisation and ban Russia from team and individual tournaments. Also, athletes from Ukraine and other nations have called on the International Olympic Committee (IOC) to suspend Russia and Belarus and ban their athletes from events immediately.
Manchester City's impressive 2-0 victory at Everton on Sunday equalled a club record of nine successive Premier League wins.
Manchester City have signed England centre back John Stones from Everton as new manager Pep Guardiola continues to reshape his side for the start of the English Premier League season.
Manchester City came from behind twice to earn a 2-2 draw with Liverpool in a breathless and pulsating Premier League encounter, at Anfield, on Sunday. All four goals came in the second half.
IMAGES from the Premier League matches played on Sunday.
Everton missed the chance to secure a place in next season's UEFA Cup when they were beaten 1-0 by Arsenal in the Premier League on Sunday.
Manchester City midfielder Kevin de Bruyne is facing a potentially lengthy spell on the sidelines after he was carried off on a stretcher with a suspected knee ligament injury in Wednesday's League Cup semi-final win over Everton.
Following is a match by match look at the English Premier League's season-opening weekend fixtures:
An own goal by Stoke City keeper Jack Butland gifted Leicester City an equaliser in a 1-1 Premier League draw at the King Power Stadium on Saturday and denied Paul Lambert's side a rare win on the road.
Tottenham Hotspur's tenacious chase of leaders Chelsea continued as they claimed a 12th consecutive Premier League home win with a 4-0 rout of Bournemouth on Saturday to cut the gap to four points.
Tottenham Hotspur beat local rivals Arsenal with second-half goals from prolific pair Dele Alli and Harry Kane on Sunday to maintain their Premier league title challenge.
Robert Huth's double and a Riyad Mahrez goal sent Premier League leaders Leicester City six points clear after a stunning 3-1 victory at shell-shocked title rivals Manchester City on Saturday.
Jose Mourinho understands why Manchester United supporters gave Marouane Fellaini a negative reception during Sunday's 1-0 win over Tottenham Hotspur but the manager will do all he can to protect the midfielder.
Arsenal will not sell striker Olivier Giroud, midfielder Jack Wilshere and winger Theo Walcott in the January transfer window despite their lack of playing time at the Premier League club, manager Arsene Wenger has said.
Images from the English Premier League matches played on Saturday
Two big derbies and an eventful weekend of football awaits us all...
All elite soccer matches in England, including the Premier League, were suspended until April 4 on Friday due to the coronavirus pandemic, English soccer's governing bodies said. The decision to suspend all football activity in the country had been jointly taken by the Premier League, the FA, the EFL and the Women's Super League (WSL), it added.
With Liverpool still to visit Chelsea, who trail them by nine points with two games in hand, Juergen Klopp's side may have to beat Brighton & Hove Albion on May 13 and rely on their superior goal difference to qualify for the Champions League, assuming they do not secure it by winning this year's trophy.
Take Norma Godinho's quiz to find out just how much you know about sport.
Here are five talking points from the weekend's action:
Manchester City begin a crucial week in the Premier League title race when they host Arsenal at the Etihad on Sunday.
Livewire striker Javier Hernandez struck six minutes from time to give Manchester United a 1-0 home win over Everton that extended their Premier League lead to nine points on Saturday.
Here are talking points from the weekend's Premier League action:
Manchester United's Marouane Fellaini contemplated leaving the club after a disappointing debut season but the towering Belgian believes he is now reaping the rewards of fighting for his place at Old Trafford.
Tottenham Hotspur's hopes of moving into the top four stalled in a 2-2 draw at bottom club Norwich City, while several VAR interventions overshadowed the action. Images from EPL matches played on Saturday.
Everton's match at home to Birmingham City and Blackpool's game against Liverpool were postponed on Sunday as Premier League fixtures once again fell victim to freezing conditions in Britain.
Former Manchester United winger Ryan Giggs has expressed his interest in the vacant managerial positions at Premier League sides Leicester City and Everton.
News of all that's transpired on and off the football field
Chelsea to host Burnley in Premier League season ope
Leicester City's Premier League title defence got off to a terrible start as they were beaten 2-1 at promoted Hull City, who shrugged off an injury crisis to shock the champions on the opening day of the new season on Saturday
Juventus rehire Allegri.
Klopp impressed with Mourinho turning Spurs into 'results machine'
Joint-leaders Tottenham Hotspur and Liverpool both dropped points on a busy day of English Premier League action as Leicester City and Southampton narrowed the gap in what is shaping up to be one of the most open title races for years.
Tottenham Hotspur routed Bournemouth 5-0 as they leapfrogged City into second place in the league, six points behind leaders Liverpool who thrashed Newcastle United 4-0.
Phil Neville scored the decisive spot kick to give Everton a 4-3 penalty shootout win over holders Chelsea after their FA Cup fourth-round replay ended in a 1-1 draw after extra time at Stamford Bridge on Saturday.
